Roli Prajapati, a six-year-old girl hailing from Noida became the youngest organ donor ever in the history of the All India Institute of Medical Sciences (AIIMS), Delhi and saved the lives of five people in April 2022. Roli Prajapati was shot in her head by unknown assailants and was admitted to AIIMS, Delhi. Doctors declared the young girl brain dead after repeated futile attempts to revive her.

“We diagnosed her to be having brain death. Subsequently, our team of doctors sat with the parents and talked about organ donation. We counselled the parents and sought their consent if they would be willing to donate organs to save the lives of other children," said Dr. Deepak Gupta, Professor of Neurosurgery and in charge of organ procurement services at the trauma centre in AIIMS, Delhi.

Despite their sorrow, Roli's parents consented to donate her organs, and her liver, kidneys, corneas, and heart valves were transplanted to the needy patients. The National Organ and Tissue Transplant Organization (NOTTO) distributed the donated organs. A seven-year-old from Lucknow received Roli's liver, while a 12-year-old received her kidneys.

In February 2020, a newborn infant who lived for only 68.3 hours donated his organs at Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh. The kidneys from the three-day boy who had irreversible brain abnormalities were given to a 21-year-old woman, saving her life. This was likely to be the country's youngest organ donation.