The first simultaneous pancreas-kidney transplant (SPK) transplant surgery on a patient with type 2 diabetes was successfully conducted for the first time at the Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh. The patient was a 54-year-old man from Roorkee who was suffering from diabetes for over a decade and was on dialysis because of kidney failure. While SPK transplant was recommended in type 1 diabetics with kidney failure, it was not recommended in type 2 diabetics with kidney failure. The thinking was that the pancreas transplant would not be useful due to the presence of insulin resistance in patients with type 2 diabetes. However, this has changed in the last few years. PGIMER has successfully performed 25 SPK transplants in patients with type 1 diabetes. This transplant for type 2 diabetes has given new hope to many patients.