Baylor St. Luke’s Medical Center in Houston, USA performed heart, lung and liver transplants during the COVID-19 outbreak as these were deemed essential procedures. The transplants in some instances were at a rate higher than before the pandemic. Between mid-March and the end of May 2020, the hospital assessed 45 patients and performed transplants for 39 of them. In comparison, for the same time period in 2019, over 85 patients were assessed and 70 transplants were performed. Multidisciplinary clinical teams developed and implemented a rigorous protocol. As a result, there was no transmission of SARS-CoV-2 and the hospital had a 100% patient survival rate. The protocol involved screening the potential patients for any signs and symptoms of COVID-19 along with a temperature check. When the patient was admitted to the hospital, a COVID-19 test as well as a CT scan of chest was done. All of those results needed to be negative in order to proceed with the transplant procedure. Potential donors also were tested for COVID-19, and further evaluated with a CT of the chest. Even in cases where the COVID-19 test was negative, if there was radiographic evidence of COVID-19 on the CT scan of the chest, that organ donation was Rejected.